Medical Imaging

EPSRC Centre for Doctoral Training

Research

Projects

  • 302 - Image-based optimisation of life-saving implanted cardiac defibrillation devices using advanced patient-specific computational whole-torso models

    Sudden cardiac death remains one of the largest killers in Western Society. Implanted cardioverter defibrillator (ICD) devices are a highly effective means of primary and secondary prevention of sudden cardiac death; however, they have a number of significant limitations. Successful defibrillation via ICDs requires very high shock energies, which limits ICD battery life, and causes significant pain and resulting psychological disorders for recipients receiving inappropriate shocks. Complications also arise from standard ICD electrodes being implanted inside the heart cavity itself. More...

  • 303 - Predicting Optimal Heart Failure Treatment with Patient Specific Models

    The LV pumps blood around the body and the location of lead that paces the LV plays a crucial role in determining CRT outcome. Evaluation of different pacing sites have found that on average pacing the LV (lateral) free wall returns better outcomes and currently represents best practice. However, a consistent finding in lead position studies is that in a significant patient cohort the LV free wall is not the optimum site and indeed some studies found it to be the worst pacing site for specific patients. More...